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Showing 2 results for “Matucci-Cerinic M”.

June 2025

EULAR recommendations for the treatment of systemic sclerosis: 2023 update

Ann Rheum Dis 2025;84:29–40 DOI: 10.1136/ard-2024-226430

Del Galdo et al. formed a new task force to update the EULAR recommendations for the pharmacological management of systemic sclerosis (SSc). The task force agreed on 22 new recommendations covering eight clinical/organ domains: Raynaud’s phenomenon (RP), digital ulcers, pulmonary arterial hypertension (PAH), musculoskeletal, skin fibrosis, interstitial lung disease (ILD), gastrointestinal, and renal crisis.

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Tocilizumab in systemic sclerosis: A randomised, double-blind, placebo-controlled, Phase 3 trial

Lancet Respir Med 2020;8:963–74 DOI: 10.1016/S2213-2600(20)30318-0.

Khanna et al. evaluated tocilizumab in patients with early diffuse cutaneous systemic sclerosis in the focuSSced trial. The primary endpoint of improved skin fibrosis was not met, but a key secondary outcome showed that tocilizumab significantly preserved lung function compared with placebo.

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